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Stabilize biological tissue samples
The StabilizorTM system uses rapid heating to preserve tissue samples as close as possible to their in vivo state. Heat stabilization permanently prevents biological changes from the moment of sampling, thereby increasing the accuracy and quality of analytical results.
- Reveal phosphorylation states and discover new endogenous peptides
- Get closer to original in vivo profiles
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Prepare, analyze and re-analyze without risk of degradation and use of additives
- minimize inter-sample variation
- improve data interpretation
Learn more about the principles of heat stabilization in the movie below.
Using the Stabilizor system:
Learn how users of the Stabilizor system have benefited from using heat stabilization in their research.
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Eliminates enzyme activity from the moment of sampling
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Stops degradation permanently - without using additives
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Standardizes sample handling - to improve reproducibility of analytical workflows
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Links upstream processing to downstream results - traceable treatment parameters
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Facilitates accurate sample comparison and data interpretation downstream
Biological samples successfully analyzed
The range of biological samples that have been heat-stabilized and analyzed successfully is expanding steadily as more scientists implement the Stabilizor system into their workflows. Currently, the benefits of heat-stabilization have been utilized when analyzing proteins or peptides in the following biological samples:
Proteins in brain, liver, heart, pancreas and breast tumor, erythrocytes and yeast.
Peptides in brain, thymus and pancreas.
Analytical techniques have included mass spectrometry,phospho-shot gun, MALDI Imaging, Western Blot with phospho-specific antibodies, 1D and 2D gels with phospho-specific stains and reversed phased protein arrays (RPPA)
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