Publications and posters

Loss of correlations among proteins in brains of the Ts65Dn mouse model of Down syndrome. Ahmed et al., J. of Proteome research. 2012. Just accepted Read more
Keywords: Down syndrome, Trisomy 21, MAP kinase, Reverse Phase Protein Array (RPPA), phospho-proteins

Extensive Characterization of Tupaia belangeri Neuropeptidome Using an Integrated Mass Spectrometric Approach. Petruzziello et al., J. Proteome Res. 2012. Read more
Keywords: Tree shrew brain (Tupaia belangeri), mass spectrometry

Sample Preparation Techniques for the Untargeted LC-MS-Based Discovery of Peptides in Complex Biological Matrices. Finoulst et al., J. Biomedicine and Biotechnology. 2011. Read more

Effect of Thaw Temperatures in Reducing Enzyme Activity in Human Thyroid Tissues. Kokkat et al., Biopreservation and Biobanking. 2011 Read more
Keywords: Human thyroid tissue, phosphatase activity

Thermal stabilization of tissues and the preservation of protein phosphorylation states for two-dimensional gel electrophoresis. Smejkal et al., Electrophoresis 2011, Volume 32, pages 2206–2215. Read more
Keywords: Mouse brain, 2D-GE, mass spectrometry

Sample Preparation in Biological Mass Spectrometry, Alexander R. Ivanov, Alexander V. Lazarev. Read more

Biomarkers of disease and post-mortem changes-heat stabilization, a necessary tool for measurement of protein regulation. Kultima et al., Journal of Proteomics, 2011. Read more

Benefits of heat-treatment to the protease packed neutrophil for proteome analysis: Halting protein degradation. Kennedy et al., Proteomics 2011, 11, pages 2560–2564 Read more
Keywords: Neutrophiles, 2D-GE, mass spectrometry

Neuropeptide profiling of the bovine hypothalamus: Thermal stabilization is an effective tool in inhibiting post-mortem degradation. Colgrave et al., Proteomics 2011, 11, 1264-1276 Read more
Keywords: Bovine brain, mass spectrometry

Methodology and technology for stabilization of specific states of signal transduction proteins. Borén M., Methods Mol Biol. 2011;717:91-100 Read more
Keywords: Mouse brain, IHC

Preserving protein profiles in tissue samples: Differing outcomes with and without heat stabilization, M Ahmed et al, Journal of Neuroscience Methods. 2011 Mar 15;196(1):99-106 Read more
Keywords: Mouse brain, Western Blot

Clinical application for the preservation of phospho-proteins through in-situ tissue stabilization, CB Rountree et al, Proteome Science, 2010; 8: 61 Read more
Keywords: Mouse brain, lung and liver, 2D-GE, Western Blot

Stopping the clock on proteomic degradation by heat-treatment at the point of tissue excision. Richard J. A. Goodwin et al. Proteomics, Volume 10, Issue 9, pages 1751-1761, No. 9 May 2010 Read more
Keywords: Mouse brain, MALDI-imaging, 2D-GE, mass spectrometry

Mass Spectrometric Imaging for Biomedical Tissue, Chughtai, K. and. Heeren, R.M.A, Analysis, Chem. Rev., 2010, 110 (5), pp 3237-3277. Read more

Neuropeptidomic analysis of the embryonic Japanese quail diencephalon, Scholz, B., H. Alm, et al., BMC Dev Biol 10: 30. Read more
Keywords: Japanese quail brain, mass spectrometry

The use of neuroproteomics in drug abuse research, M Lull et al, Drug and Alcohol Dependence, Volume 107, Issue 1, 1 February 2010, Pages 11-22 Read more

Impact of temperature dependent sampling procedures in proteomics and peptidomics - A characterization of the liver and pancreas post mortem degradome, B Scholz et al. Molecular and Cellular Proteomics, M900229-MCP200, January 28, 2010 Read more
Keywords: Mouse liver and pancreas, 2D-GE, mass spectrometry

Banking of clinical samples for proteomic biomarker studies: A consideration of logistical issues with a focus on pre-analytical variation, Jackson, D.H., and Banks, R.E., Proteomics - Clinical Applications 2010 4:3, 250-270 Read more

A report on the ESF workshop on quality control in proteomics, L Martens. Mol. BioSyst., 2010, 6, 935-938 Read more

Assessing the use of thermal treatment to preserve the intact proteomes of post-mortem heart and brain tissue, AA. Robinson et al. Proteomics., Article 2009 Oct;9(19):4433-44 Read more
Keywords: Mouse brain and heart, 2D-GE, mass spectrometry

Preserving the yeast proteome from sample degradation, J. Grassl et al. Proteomics., Proteomics. 2009 Oct;9(20):4616-26. Read more
Keywords: Yeast, 2D-GE, mass spectrometry

Development and evaluation of normalization methods for label-free relative quantification of endogenous peptides. K. Kultima, Molecular and Cellular Proteomics, October 1, 2009, 8, 2285-2295. Read more
Keywords: Mouse -, rat - and Japanese quail brain, mass spectrometry

A Quantitative Peptidomic Analysis of Peptides Related to the Endogenous Opioid and Tachykinin Systems in Nucleus Accumbens of Rats Following Naloxone-Precipitated Morphine Withdrawal U. Rossbach et al. J. Proteome Res., Proteomics. 2009 Oct;9(20):4616-26 Read more
Keywords: Rat brain, mass spectrometry

Heat Stabilization of the Tissue Proteome: A New Technology for Improved Proteomics, M. Svensson et al. J. Proteome Res., 2009, 8 (2), pp 974-981 Read more
Keywords: Mouse brain, mass spectrometry, Western Blot

Sample preparation issues for tissue imaging by imaging MS, Kaletas, B. K., I. M. van der Wiel, et al. Proteomics 9(10): 2622-33 Read more
Keywords: Human cerebellum tissue, MALDI-imaging

Protein and peptides in pictures: imaging with MALDI mass spectrometry, RJ. Goodwin et al. Proteomics., 2008 Sep;8(18):3785-800 Read more
Keywords: Mammalian tissue, MALDI-imaging

The significance of biochemical and molecular sample integrity in brain proteomics and peptidomics: stathmin 2-20 and peptides as sample quality indicators. K. Sköld et al. Proteomics. 2007 Dec;7(24):4445-56 Read more
Keywords: Mouse brain, 2D-DIGE, Western blot, mass spectrometry

Neuropeptidomics: MS Applied to the Discovery of Novel Peptides from the Brain M. Svensson et al. Anal. Chem., 2007, 79 (1), pp 14-21 Read more
Keywords: Rat and mouse brain, mass spectrometry, MALDI-imaging

Neuropeptidomics: expanding proteomics downwards. M. Svensson et al. Biochem Soc Trans 2007, 35, (Pt 3), pp 588-93. Read more
Keywords: Mouse brain, mass spectrometry, MALDI-imaging